Do I have to do this treatment for the rest of my life? The only way to effectively stop these bacteria from producing these Volatile Sulfur Compounds, is to use an Oxyd-VIII based product. No other compounds will perform this action. The bacteria reproduce every 10-12 hours and that is why the treatment must be done throughout the day. After several months, there is a residual effect, whereby the medication has a longer lasting feeling. Some patients are then able to get by with performing the procedure only twice daily, however, for the best results, most perform the procedures three times daily. Many patients use between 2-3 bottles of rinse per month. A large toothpaste lasts about 5-6 weeks. If you stop, the problems will come back again, because the bacteria will recognize the difference within a few days.